The Small GTPase Ran

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Product Description

The Ras-related nuclear protein Ran is a member of the so-called Ras-superfamily of small GTP-binding proteins and hydrolyzing proteins. A variety of edited anthologies related to the Ras-superfamily have appeared over the last decade, but Ran has been under-represented in all of them. This under-representation is not due to the fact that Ran is unimportant or non-abundant. It is almost certainly because Ran was discovered and its functions elucidated only recently, and that some of these functions may not follow the typical Ras-superfamily paradign.
Even workers in the field have difficulty keeping up with the Ran literature, and most outsiders rarely try even though they may be aware that major breakthroughs regarding the mechanisms of nuclear-cytosolic transport, mitosis and the maintenance of nuclear structure have depended upon an understanding of Ran function. The Small GTPase Ran is meant to provide specialists with a concise summary of some of the recent research in this area, along with background describing its initial identification and early characterization.

The Small GTPase Ran Review

Reviewed in Trends in Cell Biology, Vol 12, No. 4 April 2002
Frauke Melchior
Max-Planck Institute for Biochemistry, Germany"... a stimulating and interesting anthology that covers the first decade of Ran research""As a whole the book also serves as an excellent reference source because virtually all available data on Ran are covered somewhere in the book. In general, the chapters are very well written and provide valuable background information.""In conclusion, I found this book an enjoyable and instructive read and will certainly use it often as a reference in the future." Help other customers find the most helpful reviews Was this review helpful to you?�Yes No Report abuse | PermalinkComment�Comment

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